Param Adverse Reactions

Serious adverse effects: Hepatic injury.
Serious skin reactions: Acute generalised exanthematous pustulosis (AGEP); Stevens-Johnson Syndrome (SJS); Toxic epidermal necrolysis (TEN).
Allergy and hypersensitivity: Swelling of the face, mouth and throat, respiratory distress, urticaria, rash, and pruritis.
Most common adverse effects: Gastrointestinal disorder: Nausea, vomiting.
General disorders and administration site conditions: Pyrexia.
Nervous system disorders: Headache.
Psychiatric: Insomnia.
Other adverse effects in Adults: Blood and lymphatics system disorders: Anemia.
General disorders and administration site conditions: Fatigue, infusion site pain, peripheral edema.
Investigations: Aspartate aminotransferase increases breath sounds abnormal.
Metabolism and Nutrition disorders: Hypokalemia.
Musculoskeletal and connective tissue disorders: Muscle spasms, tissues.
Psychiatric disorders: Anxiety.
Respiratory, thoracic and mediastinal disorders: Dyspnea.
Vascular disorders: Hypertension, hypotension.
Other adverse effects in pediatrics: Blood and lymphatics system disorders: Anemia.
Cardiac disorders: Tachycardia.
Gastrointestinal disorder: Abdominal pain, diarrhea.
General disorders and administration site conditions: Injection site pain, peripheral edema, pyrexia.
Investigations: Hepatic enzyme increase.
Metabolism and Nutrition disorders: Hypoalbuminemia, hypokalemia, hypomagnesemia, hypophosphatemia, hypervolemia.
Musculoskeletal and connective tissue disorders: Muscle spasm, pain in extremity.
Nervous system disorders: Headache.
Psychiatric distress: Insomnia.
Renal and urinary disorders: Oliguria.
Respiratory, thoracic and mediastinal disorders: Pulmonary edema, hypoxia, pleural effusion, stridor, wheezing.
Skin and subcutaneous tissue disorders: Periorbital edema, rash.
Vascular disorders: Hypertension, hypotension.