The Paracetamol solution is administered as a 15-minute intravenous infusion.
Adolescents and adults weighing more than 50 kg: Paracetamol 1 g per administration, up to four times a day or 650 mg every 4 hours to a maximum of 4 g per day period minimum dosing interval of 4 hours.
Children, adolescents and adults weighing less than 50 kg: Paracetamol 15 mg/kg per administration, i.e. 1.5 mL solution per kg up to four times a day or 12.5 mg/kg every 4 hours to a maximum of 75 mg/kg per day. The minimum interval between each administration must be 4 hours.
Severe renal insufficiency: It is recommended, when giving Paracetamol to patients with severe renal impairment (creatinine clearance 30 mL/min), to increase the minimum interval between each administration to 6 hours.
In adults with hepatocellular insufficiency, chronic alcoholism, chronic malnutrition (low reserves of hepatic glutathione) and dehydration, the maximum daily dose must not exceed 3 g.