Favotan

5/50 mg FC tab Amlodipine camsylate 5 mg, losartan K 50 mg. 5/100 mg FC tab Amlodipine camsylate 5 mg, losartan K 100 mg

Essential HTN.

Adult Recommended dose: 1 tab daily.

May be taken with or without food: Take w/ water, preferably at the same time each day.

Hypersensitivity to amlodipine camsylate, losartan K or dihydropyridine derivatives. Patient w/ severe aortic valvular stenosis, & shock. Severe hepatic impairment. Women of childbearing potential. Pregnancy & lactation.

Discontinue if transient hypotension accompanying shock, asphyxia, & dyspnea; oligohydramnios occurs; pregnancy is confirmed. Closely observe for hypotension, oliguria & hyperkalemia. Angioedema; hyperkalemia patient. Patients w/ intravascular vol depletion; under stringent salt-restriction; bilateral or unilateral renal artery stenosis. Perform serial ultrasound exam to assess intra-amniotic environment; exchange transfusion or dialysis to reverse hypotension &/or substituting for disordered renal function. Concomitant use w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements, K-containing salt substitutes or other agents. Not to operate machines during treatment eg, driving or activities in high altitude. Mild to severe renal impairment (CrCl <20 mL/min) or dialysis patients. Not recommended in patients w/ impaired liver function. Not to be given in pregnant women & during lactation. Not recommended in ped patient <18 yr. Not recommended for initial treatment in elderly ≥75 yr.

Dizziness, headache.

Increased BP lowering effect w/ other antihypertensive agents. Losartan: Potentiated antihypertensive effects w/ hydrochlorothiazide. Decreased conc w/ rifampin. Decreased active metabolite conc & increased conc w/ fluconazole. Increased serum K w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or K-containing salt substitutes. Further deterioration of renal function w/ NSAIDs including selective COX-2 inhibitors.

Angiotensin II Antagonists

C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.

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