Sianem Adverse Reactions

Gastrointestinal: Nausea, vomiting, diarrhea, pseudomembranous colitis, hemorrhagic colitis, staining of the teeth and/or tongue, gastroenteritis, abdominal pain, glossitis, papillar hypertrophy of the tongue, heartburn, pharyngeal pain, increased salivation, and taste perversion.
Central nervous system: Fever, seizure, dizziness, somnolence, tremor, confusion, myoclonus, paresthesia, vertigo, headache, myoclonus, encephalopathy, Psychic disturbances including hallucinations.
Dermatologic: Rash, pruritus, urticaria, allergic dermatitis, erythema multiforme, Stevens-Johnson syndrome, angioedema, toxic epidermal necrolysis, flushing, cyanosis, candidiasis, hyperhidrosis, pruritus vulvae, pain and erythema at injection site, phlebitis.
Hematologic: Eosinophilia, leucopenia, neutropenia, agranulocytosis, pancytopenia, thrombocytopenia, bone marrow depression, hemolytic anemia.
Renal: Increases in BUN and/or serum creatinine concentration, oliguria/anuria, polyuria, discoloration of urine, proteinuria, acute renal failure.
Hepatic: Increases in serum concentrations of AST, ALT, alkaline phosphatase, LDH, and bilirubin, jaundice, hepatitis.
Respiratory system: Chest discomfort, dyspnea, hyperventilation, thoracic spine pain.
Cardiovascular: Hypotension, palpitation, tachycardia.
Others: Hearing loss, tinnitus, polyarthralgia.