Ataxia, clonic seizures, and death were reported in mice. Who received an overdose may have central nervous system symptoms such as confusion or seizure.
Treatment: In acute overdosage, the drug should be discontinued immediately and the patient should be treated symptomatically (including supportive measures). Although Imipenem and Cilastatin sodium is hemodialyzable, but the usefulness of this procedure in enhancing the elimination of Imipenem and Cilastatin sodium is questionable.