Felodipine can, like other vasodilators, cause hypotension. This may in susceptible patients result in myocardial ischemia.
Mild gingival enlargement has been reported in patients with pronounced gingivitis/periodontitis. The enlargement can be avoided or reversed by careful dental hygiene.
Plendil contains lactose and should not be given to patients with hereditary galactose intolerance or glucose-galactose malabsorption.
Effects on ability to drive and use machines: As dizziness and fatigue may occur in connection with Plendil treatment, this should be considered when enhanced attention is required, for example, when driving or operating machines.