Dicofen Adverse Reactions

Gastrointestinal Tract: Occasional: Epigastric [pain, nausea, vomiting, diarrhea, abdominal cramps, dyspepsia, flatulence, anorexia. Rare: Gastrointestinal bleeding (hematemesis, melema, bloody diarrhea), gastric or intestinal ulcer with or without bleeding or perforation. Isolated Cases: Aphthous stomatitis, glossitis, esophageal lesions, diaphragm-like intestinal strictures, lower gut disorders e.g., nonspecific hemorrhagic colitis and exacerbation of ulcerative colitis or Crohn's disease; constipation, pancreatitis.
Central Nervous System: Occasional: Headache, dizziness, vertigo. Rare: Drowsiness.
Isolated Cases: Sensory disturbances, including paresthesias, memory disturbances, disorientation, insomia irritability, convulsions, depression, anxiety, nightmares, tremor, psychotic reactions, aseptic meningitis.
Special Senses: Isolated Cases: Disturbances of vision (blurred vision, diplopia), impaired hearing, tinnitus, taste disturbances.
Skin: Occasional: Rashes. Rare: Urticaria. Isolated Cases: Bullous eruptions, eczema, erythema multiforme, Stevens-Johnson syndrome, Lyell's syndrome (acute toxic epidermolysis), erythroderma (exfoliative dermatitis), loss of hair, photosensitivity reaction, purpura, including allergic purpura.
Kidney: Rare: Edema: Isolated Cases: Acute renal failure, urinary abnormalities, eg hematuria and proteinuria, interstitial nephritis nephrotic syndrome, papillary necrosis.
Liver: Occasional: Elevation of serum aminotransferase enzymes. Rare: Hepatitis with or without jaundice. Isolated Cases: Fluminant hepatitis.
Blood: Isolated Cases: Thrombocytopenia, leucopenia, hemolytic anemia, aplastic anemia, agranulocytosis.
Hypersensitivity: Rare: Hypersensitivity reactions eg, asthma, systemic anaphylactic/ anaphylactoid reactions including hypotension. Isolated Cases: Vasculitis, pneumonitis.
Cardiovascular System: Isolated Cases: Palpitation, chest pain, hypertension, congestive failure.
Other Organ System: Rare: Edema, injection site disorders in cases of injection administration (eg, local pain and induration; In Isolated Cases: Abscesses and local necrosis). Isolated Cases: Impotence (associated with Diclofenac sodium intake is doubtful), palpitation, chest pain, hypertension.