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Management of acute poisoning with non-steroidal anti-inflammatory agents consists essentially of supportive and symptomatic measures. There is no typical clinical picture resulting from an overdosage of Diclofenac.
The therapeutic measures to be taken in cases of overdosage are as follows: Absorption should be prevented as soon as possible after overdosage with Diclofenac sodium tablet by means of gastric lavage and activated charcoal.
Supportive and symptomatic treatment should be given for complications eg, hypotension, renal failure, convulsions, gastrointestinal irritation and respiratory depression.
Specific therapies e.g., forced diuresis, dialysis or hemoperfusion are unlikely to be helpful in accelerating the elimination NSAIDs, because of their high protein-binding rate and extensive metabolism.
