Diclofenac, a phenylacetic derivative, is an NSAID. It is used mainly as the sodium salt for the relief of pain and inflammation in various conditions: musculoskeletal and joint disorders such as rheumatoid arthritis, osteoarthritis and ankylosing spondylitis; peri-articular disorders, such as sprains and strains; and other painful conditions such as renal colic, acute gout, dysmenorrheal, migraine and following some surgical procedures. It has also been used in some countries for the management of actinic keratoses and fever.