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Antacids: Coadministration of gabapentin with antacid reduced gabapentin bioavailability by about 20%.
It is recommended that gabapentin be taken at least 2 hours following antacid administration.
Cimetidine: Cimetidine alters the renal excretion of gabapentin. This small decrease in gabapentin excretion is not expected to be of clinical importance.
