Because of the possibility of increased seizure frequency, anticonvulsant drugs, including gabapentin, should not be discontinued suddenly.
Gabapentin is not generally considered effective in the treatment of absence seizures. In combination treatment with morphine, these patients should be carefully observed for signs of CNS depression, such as somnolence, and the dose of gabapentin or morphine should be reduced appropriately.
Effects on ability to drive and use machines: Gabapentin can produce drowsiness and dizziness, and patients should be cautioned that the drug may impair their ability to perform activities such as operating machinery or operating a motor vehicle.