Acute sinusitis 500 mg once daily for 10-14 days or 750 mg once daily for 5 days.
Acute exacerbation of chronic bronchitis 500 mg once daily for 7 days or 750 mg once daily for 5 days.
Community-acquired pneumonia 500 mg once daily for 7-14 days or 750 mg once daily for 5 days.
Complicated UTI, pyelonephritis 250 mg once daily for 10 days or 750 mg once daily for 5 days.
Nosocomial pneumonia, complicated skin & skin structure infections 750 mg once daily for 7-14 days.
Uncomplicated skin & skin structure infections 500 mg once daily for 7-10 days.
Chronic bacterial prostatitis 500 mg once daily for 28 days.
Uncomplicated UTI 250 mg once daily for 3 days.
Renal impairment Acute sinusitis & exacerbation of chronic bronchitis, community-acquired pneumonia, uncomplicated skin & skin structure infections, chronic bacterial prostatitis CrCl 20-49 mL/min Initially 500 mg, then 250 mg once daily,
10-19 mL/min, hemodialysis or CAPD patients Initially 500 mg dose, then 250 mg every 48 hr.
Complicated skin & skin structure infections, nosocomial pneumonia, community-acquired pneumonia CrCl 20-49 mL/min Initially 750 mg, then 750 mg every 48 hr,
10-19 mL/min, hemodialysis or CAPD patients Initially 750 mg dose, then 500 mg every 48 hr.
Complicated UTI, acute pyelonephritis CrCl 10-19 mL/min Initially 250 mg, then 250 mg every 48 hr.
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