Ecoxib Adverse Reactions

1% to 10%: Cardiovascular: Edema, hypertension, palpitations.
Central nervous system: Dizziness, fatigue, headache.
Dermatologic: Bruising.
Gastrointestinal: Abdominal pain, diarrhea, dyspepsia, flatulence, heartburn, nausea.
Hepatic: ALT increased, AST increased.
Neuromuscular & skeletal: Weakness.
Miscellaneous: Alveolar osteitis, flu-like syndrome.
<1%, postmarketing and/or case reports: Abnormal taste, anaphylactic/anaphylactoid reactions, anemia, angina pectoris, angioedema, anxiety, appetite increase/decrease, arrhythmia, atrial fibrillation, blurred vision, bronchospasm, BUN increased, cerebrovascular accident, chest pain, confusion, congestive heart failure, conjunctivitis, constipation, cough, CPK increased, depression, dyspnea, ECG changes, epistaxis, esophagitis, erythema, facial edema, fixed drug eruption, flushing, gastritis, gastroduodenal ulcer, gastroenteritis, gastroesophageal reflux, gastrointestinal bleeding, gastrointestinal perforation, hallucinations, hepatic failure, hepatitis, hyperkalemia, hypersensitivity reactions, hypertensive crisis, hypoesthesia, hyponatremia, insomnia, interstitial nephritis, jaundice, leukopenia, MI, muscle pain, muscle spasm, nephrotic syndrome, oral ulceration, pancreatitis, paresthesia, peptic ulcers, proteinuria, pruritus, rash, renal insufficiency (including renal failure), serum creatinine increased, shock, somnolence, Stevens-Johnson syndrome (SJS), tachycardia, taste abnormal, thrombocytopenia, tinnitus, toxic epidermal necrolysis (TEN), transient ischemic attack, upper respiratory infection, uric acid levels increased, urinary tract infection, urticaria, vasculitis, vertigo, vomiting, weight gain, xerostomia.